Azathioprine
Azathioprine is a drug that suppresses the immune system. It is mainly used in people suffering from autoimmune diseases or organ transplants. However, azathioprine can also be useful for dogs in some cases. In this article, you will find out what azathioprine is, how it works and what its advantages and disadvantages are.
What is azathioprine?
Azathioprine is a so-called immunosuppressant, i.e. it inhibits the activity of the body's own defense system. It is one of the active substances known as purine analogs. These are substances that disrupt the formation of DNA and RNA. This prevents the multiplication of cells that are responsible for the immune response.
How does azathioprine work in dogs?
Azathioprine is used in dogs primarily for diseases caused by an overreaction of the immune system. These include, for example
- Autoimmune diseases such as lupus erythematosus, rheumatoid arthritis or hemolytic anemia
- Chronic inflammations such as Crohn's disease or ulcerative colitis
- Rejection reactions after organ transplants
Azathioprine does not take effect immediately, but only after a few weeks. It must therefore be administered regularly and on a long-term basis. The dosage depends on the dog's weight and state of health and must be determined by the vet.
What are the benefits of azathioprine in dogs?
Azathioprine can provide symptom relief in dogs with severe or life-threatening conditions. It can improve the quality of life and life expectancy of affected animals. Azathioprine can also be used in combination with other medications to reduce the dose or increase the effectiveness.
What are the disadvantages of azathioprine in dogs?
Azathioprine is a very strong drug that can also have many side effects. The most common are:
- Nausea and vomiting
- diarrhea
- Loss of appetite and weight loss
- Blood count changes such as anemia or leukopenia
- susceptibility to infections
- Liver or kidney damage
- Hair loss or skin rash
- Risk of cancer
To avoid or minimize these side effects, the dog must be regularly examined by a vet. Blood tests are carried out to check the function of the organs and the immune system. The dose of azathioprine may need to be adjusted or discontinued.
Azathioprine is a drug that suppresses the immune system. It can help to alleviate symptoms and improve quality of life in dogs with certain diseases. However, azathioprine also has many side effects that require careful monitoring by a veterinarian. Azathioprine should therefore only be administered after an accurate diagnosis and under professional guidance.
The authors assume that a veterinarian should be consulted if an animal is ill and that medication should only be taken after consultation with a doctor or pharmacist. Only an individual examination can lead to a diagnosis and treatment decision.
We help you find the nearest vet → This way